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Using OxyContin with medicines which can be CYP3A4 inhibitors or discontinuation of CYP3A4 inducers may end up in a lethal overdose of oxycodone.five The incidence of side effects like nausea, vomiting, itching, or drowsiness had been identical; nevertheless, constipation was more prone to be skilled by persons having hydrocodone patients (21% of h

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